<?xml version="1.0" encoding="UTF-8"?>
<article article-type="research-article" dtd-version="1.3" xml:lang="en">
  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>Czech and Slovak Ophthalmology</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">491</article-id>
      <article-categories>
        <subj-group>
          <subject>Original article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Retinal Tamponade with Silicone Oil – Long Term Results</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Jančo</surname>
            <given-names>Ladislav</given-names>
          </name>
          <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8114-0974</contrib-id>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Takáčová</surname>
            <given-names>Adriana</given-names>
          </name>
          <contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-2802-6490</contrib-id>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Ondrejková</surname>
            <given-names>Marta</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Vida</surname>
            <given-names>Rastislav</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Bartoš</surname>
            <given-names>Marcel</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Mesárošová</surname>
            <given-names>Mária</given-names>
          </name>
        </contrib>
      </contrib-group>
      <pub-date date-type="pub" publication-format="electronic">
        <day>18</day>
        <month>9</month>
        <year>2014</year>
      </pub-date>
      <issue>5</issue>
      <elocation-id>2</elocation-id>
      <abstract>
        <p>Aim: The aim of this study is to evaluate the frequency and efficacy of silicone oil (SO) retinal tamponade in various retinal diseases. The incidence of silicone oil tamponade according to individual indications, incidence of complications and duration of tamponade were evaluated in the study. Material and Methods : A retrospective study included 510 eyes that were operated on pars plana vitrectomy (PPV) from January 2010 to December 2012. In our group we evaluated 241 men and 189 women, age 4-84 years, mean 62 years . Follow-up period was 12 to 48 months, an average of 27.5 months . We evaluated 253 eyes with diabetic retinopathy, 201 eyes with regmatogenous retinal detachment, 34 eyes with endophthalmitis and 22 eyes after the injury. Results: In 253 diabetic retinopathy eyes (DR) silicone oil tamponade was indicated in 56 eyes (22.1 %). Silicone oil removal was done on 22 eyes (39.3 %), the average lengthof SO tamponade was 9.7 months. After SO removal BCVA (best corrected visual acuity) 0,1 and worse had 12 eyes (54,6 %), 0,2 – 0,4 had 5 eyes (22,7 %) and 0,5 or better had 5 eyes (22,7 %). Permanent SO tamponade was left in 34 diabetic retinopathy eyes (60.7 %). Secondary glaucoma (SG) was present in 40 eyes (71.5 %). In 201 retinal detachment (RD) eyes silicone oil tamponade was used in 76 eyes (37.8 %). Secondary glaucoma was present in 31 eyes (40.8 %). Silicone oil was successfully removed in 40 eyes (52.6 %), the average length of tamponade was 9.2 months. In this group BCVA 0,1 and worse had 22 eyes (55,0 %), 0,2 – 0,4 had 15 eyes (37,5 %) and 0,5 or better had 3 eyes (7,5 %). 36 eyes (47,4 %) RD eyes had permanent silicone oil tamponade. In a group of 34 eyes with endophthalmitis SO tamponade was used in 16 eyes (47 %). Secondary glaucoma was present in 3 eyes (18.8 %). Silicone oil removal we did in 11 eyes (68.8 %), the average length of SO tamponade was 5.5 months. After SO removal BCVA 0,1 and worse had 3 eyes (27,2 %), 0,2 – 0,4 had 4 eyes (36,4 %) and 0,5 or better had 4 eyes (36,4 %). 5 eyes (31.2 %) with endophthalmitis had permanent SO tamponade. Out of 22 eyes with eye injuries SO tamponade was used in 14 eyes (63.6 %). 5 eyes (35.7 %) had secondary glaucoma. In 9 eyes (64.3 %) silicone oil was removed, the average length of tamponade was 9.1 months. In this group BCVA 0,1 and worse had 6 eyes (66,7 %), 0,2–0,4 had 1 eye (11,1 %) and 0,5 or better had 2 eyes (22,2 %). Permanent silicone oil tamponade had 5 eyes (35,7 %). In group of 56 phakic eyes (100 %) with silicone oil tamponade we followed cataract progression. 26 eyes (40 %) had cataract surgery in 6 month follow up, 47 eyes (72.3 %) in 1 year follow up and 57 eyes (87.7 %) had cataract surgery in 3 years follow up. Conclusion: Silicone oil tamponade is the method of choice for long-term and stable retinal tamponade, which is important for good functional outcomes of the surgical intervention. The silicone oil tamponade of the retina is nowadays irreplaceable, despite of its potential risks and complications.</p>
      </abstract>
      <kwd-group>
        <kwd>keratoconus</kwd>
        <kwd>corneal cross-linking</kwd>
        <kwd>riboflavin</kwd>
        <kwd>UVA irradiation</kwd>
        <kwd>maximum curvature of the cornea</kwd>
        <kwd>effectivity of the treatment</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <back>
    <ref-list>
      <title>References</title>
      <ref id="R11290">
        <mixed-citation>Abrams, G.W., Azen, S.P., Barr, C.C. et al.: The incidence of corneal abnor- malities in the Silicone Study. Silico- ne Study report 7. Arch Ophthalmol, 1995; 113:764–769.</mixed-citation>
      </ref>
      <ref id="R11291">
        <mixed-citation>Dayani, P.N., Chow, J., Stinnett, S.S., Jaffe, G.J.: Pars plana vitrectomy, flu- ocinolone acetonide implantation, and silicone oil infusion for the treatment of chronic, refractory uveitic hypotony. Am J Ophthalmol, 2011; 152:849–856.</mixed-citation>
      </ref>
      <ref id="R11292">
        <mixed-citation>Doležalová, J., Rusňák, Říčařová, R., Karel, I.: Lze úspěšně léčit těžké perforující poranění? Čes a slov Oftal, 2004; 2: 118–123.</mixed-citation>
      </ref>
      <ref id="R11293">
        <mixed-citation>Dotfielová, D., Dvořák, J., Kalvodová, B., Štěpánková, J.: Pars plana vitrektomie s primární implantací silikonového oleje v léčbě akutní exogenní endoftalmitidy na očích bez odchlípení sítnice. Čes a slov Oftal, 2003, 3, 146–152.</mixed-citation>
      </ref>
      <ref id="R11294">
        <mixed-citation>Ernest, J., Rejmont, L.: Fakoemulzifikace u očí po pars plana vitrektomii s implantací silikonového oleje. Čes a slov Oftal, 1999; 2: 82–85.</mixed-citation>
      </ref>
      <ref id="R11295">
        <mixed-citation>Falkner, C.I., Binder, S., Kruger, A.: Outcome after silicone oil removal. Br J Ophthalmol, 2001; 85: 1324–1327.</mixed-citation>
      </ref>
      <ref id="R11296">
        <mixed-citation>Herbert, E.N., Laidlaw, D.A., Williamson, T.H.: Loss of vision once silicone oil has been removed. Retina, 2005; 25: 808–809.</mixed-citation>
      </ref>
      <ref id="R11297">
        <mixed-citation>Honavar, S.G., Goyal, M., Majji A.B. et al.: Glaucoma after pars plana vitrectomy and silicone oil injection for complicated retinal detachments. Ophthalmology, 1999; 106: 169–176.</mixed-citation>
      </ref>
      <ref id="R11298">
        <mixed-citation>Hutton, W.L., Azen, S.P., Blumenkranz M.S. et al.: The effects of silicone oil removal. Silicone Study Report 6. Arch Ophthalmol, 1994; 112: 778–785.</mixed-citation>
      </ref>
      <ref id="R11299">
        <mixed-citation>Chan, C.K., Tarasewicz, D.G.: Subconjunctival migration of silicone oil through a Baerveltd pars plana glaucoma implant. Br J Ophthalmol, 2005; 89: 240–241.</mixed-citation>
      </ref>
      <ref id="R11300">
        <mixed-citation>Charles, S., Randolph, J.C., Sigler, E.J.: Pars plana vitrectomy reoperation without removing silicone oil. Retina, 2012; 32: 1664–1665.</mixed-citation>
      </ref>
      <ref id="R11301">
        <mixed-citation>Jackson, T.L., Thiagarajan, M., Murthy, R. et al.: Pupil block glaucoma in phakic and pseudophakic patients after vitrectomy with silicone oil injection. Am J Ophthalmol, 2001; 132: 414–416.</mixed-citation>
      </ref>
      <ref id="R11302">
        <mixed-citation>Jonas, J.B., Knorr, H.L., Rank, R.M. et al.: Retinal redetachment after removal of intraocular silicone oil tamponade. Br J Ophthalmol, 2001; 85: 1203–1207.</mixed-citation>
      </ref>
      <ref id="R11303">
        <mixed-citation>Karel, I., Michaličková, M., Kuthan, P.: Dlouhodobé výsledky pars plana vitrektomie a silikonového oleje u obrovských trhlin sítnice dětského věku. Čes a Slov Oftal, 1997; 3: 147–154.</mixed-citation>
      </ref>
      <ref id="R11304">
        <mixed-citation>Lakits, A., Nennadal, T., Scholda, C. et al.: Chemical stability of silicone oil in the human eye after prolonged clinical use. Ophthalmology 1999; 106: 1091–1100.</mixed-citation>
      </ref>
      <ref id="R11305">
        <mixed-citation>Mancino, R., Ciuffoletti, E., Martucci, A., Aiello, P., Cedrone, C., Cerulli, L., Nucci, C.: Anatomical and functional results of macular hole retinal detachment surgery in patients with high myopia and posterior staphyloma treated with perfluoropropane gas or silicone oil. Retina, 2013; 33: 586–592.</mixed-citation>
      </ref>
      <ref id="R11306">
        <mixed-citation>Romano, M.R., Angi, M., Romano, V., Parmeggiani, F., Campa, C., Valldeperas, X., Costagliola, C.: Intraocular pressure changes following the use of silicone oil or Densiron 68 as endotamponade in pars plana vitrectomy. Clin Ophthalmol, 2010; 4: 1391–1396.</mixed-citation>
      </ref>
      <ref id="R11307">
        <mixed-citation>Scott, I.U., Flynn, H.W., Jr., Murray, T.G. et al.: Outcomes of complex retinal detachment repair using 1000- vs 5000 centistoke silicone oil. Arch Ophthalmol, 2005; 123: 473–478.</mixed-citation>
      </ref>
      <ref id="R11308">
        <mixed-citation>Strmeň, P., Brósková, D., Vavrová, K., Hasa, J., Krásnik, V. Glaukómy u pacientov po pars plana vitrektómii pre proliferatívnu diabetickú retinopatiu. Choroby hlavy a krku, 1995; 4, 1: 39–42.</mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>
