<?xml version="1.0" encoding="UTF-8"?>
<article article-type="research-article" dtd-version="1.3" xml:lang="en">
  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>Czech and Slovak Ophthalmology</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">75</article-id>
      <article-categories>
        <subj-group>
          <subject>Original article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Trends in Indications of Perforating Keratoplasty at the Department of Ophthalmology, Faculty Hospital, Brno during the Period 2008-2012</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Rybárová</surname>
            <given-names>Naďa</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Vlková</surname>
            <given-names>Eva</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Pirnerová</surname>
            <given-names>Lenka</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Trnková</surname>
            <given-names>Věra</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Machačová</surname>
            <given-names>Hana</given-names>
          </name>
        </contrib>
      </contrib-group>
      <pub-date date-type="pub" publication-format="electronic">
        <day>30</day>
        <month>1</month>
        <year>2015</year>
      </pub-date>
      <issue>1</issue>
      <elocation-id>2</elocation-id>
      <abstract>
        <p>Introduction: The aim of the study is retrospective analysis of perforating keratoplasty (PKP) indications at the Department of Ophthalmology, Faculty Hospital, Masaryk University, Brno, Czech Republic, E.U., during the period of 5 years, from January 1st, 2008 to December 31st, 2012. Material and Methods: We performed the PKP indications’ retrospective analysis at the Department of Ophthalmology, Faculty Hospital, Masaryk University, Brno, Czech Republic, E.U., during the period of 5 years, from January 1st, 2008 to December 31st, 2012, with complex evaluation of demographic and clinical data. The clinical diagnoses indicating the perforating keratoplasty were divided into 6 groups (keratoconus, bulous keratopathy, keratitis, corneal dystrophies, injuries, corneal transplant failure, and others) according to Cunningham et al. 2011 (2) and Boimer et al. 2012(1) methods. Results: Our results correspond to data in the literature published abroad, where the majority of recently published papers refer significant increase of corneal transplant failure in the last years of follow-up.</p>
      </abstract>
      <kwd-group>
        <kwd>perforating keratoplasty</kwd>
        <kwd>indications</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <back>
    <ref-list>
      <title>References</title>
      <ref id="R10080">
        <mixed-citation>Boimer, C., Lee, K., Sharpen, L., Mashour, RS. et al.: Evolving surgical techniques of and indications for corneal transplantation in Ontario from 2000 to 2009. Can J Ophthalmol, 46, 2011, 4: 360–366.</mixed-citation>
      </ref>
      <ref id="R10081">
        <mixed-citation>Cunningham, WJ., Brookes, NH., Twohill, HC. et al.: Trends in the distribution 1997, 3: 163–168.</mixed-citation>
      </ref>
      <ref id="R10082">
        <mixed-citation>Dandona, L., Ragu, K., Janarthanan, M. et al.: Indications for penetrating keratoplasty in India. Indian J Ophthalmol, 45,</mixed-citation>
      </ref>
      <ref id="R10083">
        <mixed-citation>Dobbins, KR., Price, FW Jr., Whitson, WE.: Trends in the indications for penetrating keratoplasty in the midwestern United States. Cornea, 19, 2000, 6: 813– 816.</mixed-citation>
      </ref>
      <ref id="R10084">
        <mixed-citation>Galvis, V., Tello, A., Gomez, AJ. et al.: Corneal Transplantation at an Ophthal- ons, outcomes, and complications. Eye (Lond)., 23, 2009, 6: 1288–1294.</mixed-citation>
      </ref>
      <ref id="R10085">
        <mixed-citation>Ghosheh, FR., Cremona, FA., Rapuano, ChJ. et al.: Trends in penetrating keratoplasty in the United States 1980–2005. Int J Ophtalmol, 2008, 28: 147–153.</mixed-citation>
      </ref>
      <ref id="R10086">
        <mixed-citation>Jirásková, N., Rozsíval, P., Urminský, J.: Klinické výsledky 100 transplantácií rohovky. Čes a slov Oftal, 55, 1999, 6: 355–358.</mixed-citation>
      </ref>
      <ref id="R10087">
        <mixed-citation>Lois, N., Kowal, VO., Cohen, EJ., Rapuano, CJ. et al.: Indications for penetrating keratoplasty and associated procedures 1989–1995. Cornea, 16, 1997, 6: 623–</mixed-citation>
      </ref>
      <ref id="R10088">
        <mixed-citation>Módis, L Jr., Szalai, E., Facskó, A. et al: Corneal transplantation in Hungary (1946–2009). Clin Experiment Ophthalmol, 39, 2011, 6: 520–525.</mixed-citation>
      </ref>
      <ref id="R10089">
        <mixed-citation>Rahman, I., Carley, F., Hillarby, C. et al.: Penetrating keratoplasty: indicatiratoplastika. Brno, Masarykova Univerzita, 1999, 76 s.</mixed-citation>
      </ref>
      <ref id="R10090">
        <mixed-citation>Siganos, CS., Tsiklis, NS., Miltsakakis, DG. et al.: Changing indications for penetrating keratoplasty in Greece, 1982– 2006: a multicenter study. Cornea, 29, 2010, 4: 372–374.</mixed-citation>
      </ref>
      <ref id="R10091">
        <mixed-citation>Sundmacher, R., Reinhard, T.: Ciclosporin A in perforating keratoplasty. Čes a slov Oftal, 51, 1995, 5:271–276.</mixed-citation>
      </ref>
      <ref id="R10092">
        <mixed-citation>Tilahun, Y., Shimelash, D.: The outcome of corneal transplantation versus indications in a tertiary eye care center in Ethiopia. Ethiop Med J, 48, 2010 Jan, 1: 35–39.</mixed-citation>
      </ref>
      <ref id="R10093">
        <mixed-citation>Ting, DS., Sau, CY., Srinivasan, S., Ramaesh, K. et al: Changing trends in keratoplasty in the West of Scotland: a 10- year review. Br J Ophthalmol, 96, 2012, 3: 405–408.</mixed-citation>
      </ref>
      <ref id="R10094">
        <mixed-citation>Vlková, E., Hlinomazová, Z.: Riziková ke - mological Referral Center in Colombia: Indications and Techniques (2004–2011). Open Ophthalmol J, 2013, 7: 30–33.</mixed-citation>
      </ref>
      <ref id="R10095">
        <mixed-citation>Wang , J., Hasenfus, A., Schirra, F. et al.: Changing indications for penetrating keratoplasty in Homburg/Saar from 2001 to 2010 – histopathology of 1,200 corneal buttons. Graefes Arch Clin Exp Ophthalmol, 251, 2013, 3: 797–802.</mixed-citation>
      </ref>
      <ref id="R10096">
        <mixed-citation>Wang, JY., Xie, LX., Song, XS., Zhao, J.: Trends in the indications for penetrating keratoplasty in Shandong, 2005–2010. Int J Ophthalmol, 4, 2011, 5: 492–497.</mixed-citation>
      </ref>
      <ref id="R10097">
        <mixed-citation>Xie, L., Song, Z., Zhao, J. et al: Indications for penetrating keratoplasty in north China. Cornea, 26, 2007, 9: 1070–1073.</mixed-citation>
      </ref>
      <ref id="R10098">
        <mixed-citation>Zare, M., Javadi, M.A., Einollahi, B. et al.: Changing indications and sirgical techniques for corneal transplantation between 2004 and 2009 at a tertiary refferal center. Middle East Afr J Ophthalmol, 2012, 19: 323–329.</mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>
